The article discusses how Cas12a, a molecular tool used for genetic editing, behaves differently based on the concentration of magnesium ions. In high magnesium conditions, Cas12a faces challenges in precision editing, especially when dealing with specific errors in the genetic instructions. The study emphasizes the importance of understanding these conditions for the effective use of Cas12a in genome editing and biotechnology applications.
My work for this article is an animated cover to illustrate that illustrate this concept, showing liquid magnesium shielding a strand of DNA from being edited by CRISPR scissors